CHEM 438 — Medicinal Chemistry
Chemistry · University of Ghana
Definition of Medicinal Chemistry. Classification of Drugs. Principles of drug action: Pharmacodynamics, pharmacokinetics and pharmacogenetics. Agonists and Antagonists; the Receptor Theory. Drug absorption, distribution and excretion; Bioavailability and bioequivalence. Drug Metabolism - Phase I and Phase II reactions, toxicity (ADMET). Structure-Activity Relationships (excluding quantitative SAR). Specific Drug Types - their chemistry and pharmacology. (A selection will be made each year from the following: Barbiturates, Antibacterial Agents - sulphonamides, Antibiotics including Penicillins and Tetracyclines; Antiviral drugs, including anti-retrovirals (anti-HIV drugs); Antimalarials including the artemisinin-based drugs.);Pesticides - Pyrethroids, DDT and related compounds, organophosphates, naturally occurring pesticides;Drug Development, including development from natural sources. Quality Assurance and good manufacturing practices.
- Credits
- 2
- Level
- Level 400
- Semester
- Semester One
Other courses on this programme
- CHEM 114 — Practical II
- CHEM 401 — Thermodynamics II
- CHEM 402 — Quantum Chemistry
- CHEM 403 — Symmetry, Group Theory, and Applications
- CHEM 405 — Reaction Kinetics
- CHEM 418 — Photochemistry
- CHEM 423 — Polymer Chemistry and Technology
- CHEM 424 — Molecular Spectroscopy
- CHEM 439 — Organometallic Chemistry
- CHEM 441 — Chemistry of Natural Products
- CHEM 452 — Solid State Chemistry
- CHEM 454 — Transition Metal Chemistry
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Start freeCourse details from University of Ghana Volume 3 Handbook for the Bachelor's Degree: Course Descriptions for Programmes in the Sciences (2017).