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BCMB 301 — Intermediary Metabolism

Biochemistry, Cell and Molecular Biology · University of Ghana

Carbohydrates: Digestion of carbohydrates, glycolysis and fate of pyruvate in different organisms; tricarboxylic acid (TCA) cycle; pentose phosphate pathway and fate of reduced coenzymes; catabolism of monosaccharides other than glucose; gluconeogenesis, Calvin Benson cycle, Cori cycle, glyoxylate cycle; glycogenesis and glycogenolysis; regulation of carbohydrate metabolism; Diseases of carbohydrate metabolism. Lipids: Digestion of triacylglycerols; the different lipases (lipoprotein lipase, hormonesensitive lipase); fate of glycerol; beta-oxidation of fatty acids; fate of products (acetyl and propionyl CoA, ketone bodies, reduced coenzymes); synthesis of fatty acids triacylglycerol, cholesterol; regulation of metabolism. Amino acids: Digestion of proteins, transamination, deamination and decarboxylation of amino acids and the fate of ammonia (urea cycle) and carbon skeleton; metabolism of specific amino acids (aromatic and sulphur-containing amino acids); synthesis of amino acids; in-born errors of amino acid metabolism; regulation of metabolism. Energetics: Free energy and biochemical reactions (spontaneity, anabolic and catabolic reactions); metabolic reactions and ATP; energy of hydrolysis of ATP, ADP and phosphorylation products; ATP production (substrate level and oxidative phosphorylation, photophosphorylation, C3, C4); coupling reactions; uncoupling agents.

Credits
3
Level
Level 300
Semester
Semester One

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Course details from University of Ghana Volume 3 Handbook for the Bachelor's Degree: Course Descriptions for Programmes in the Sciences (2017).