BCMB 303 — Molecular Biology I
Biochemistry, Cell and Molecular Biology · University of Ghana
Purine and pyrimidine biosynthesis: Regulation of biosynthesis. Structure and properties of nucleosides and nucleotides. Biosynthesis of deoxyribonucleotides; thymidylate biosynthesis. Salvage pathways. DNA and chromosome structure: Evidence for DNA as carrier of genetic information. Primary and secondary (A, B and Z DNA) and tertiary structure of DNA. Elucidation of DNA structure. Watson and Crick double helix. Structural differences between RNA and DNA. Methods for sequencing DNA. Organisation of DNA in chromosomes, nucleosome structure. DNA replication: Mechanism of replication (prokaryotic and eukaryotic). Evidence for semiconservative replication. DNA replicating enzymes. Directionality of replication. Transcription: Mechanism of transcription (prokaryotic and eukaryotic). Features of a typical transcription unit. Characteristics of different types of RNA. Modification and processing RNA. Reverse transcription.
- Credits
- 2
- Level
- Level 300
- Semester
- Semester One
Other courses on this programme
- BCMB 301 — Intermediary Metabolism
- BCMB 302 — Cell Biology II
- BCMB 304 — Molecular Biology II
- BCMB 305 — Biochemistry of Hormones
- BCMB 306 — Integration and Control of Metabolism
- BCMB 307 — Data Handling & Interpretation
- BCMB 308 — Bioenergetics
- BCMB 309 — Principles of Lab Organization & Management
- BCMB 311 — Practical Biochemistry II
- BCMB 312 — Cell & Molecular Biology Practical I
- BCMB 313 — Biochemistry of Viruses
- BCMB 314 — Membrane Biochemistry
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Start freeCourse details from University of Ghana Volume 3 Handbook for the Bachelor's Degree: Course Descriptions for Programmes in the Sciences (2017).