BCMB 314 — Membrane Biochemistry
Biochemistry, Cell and Molecular Biology · University of Ghana
Introduction: Membrane types and functions; chemical composition (lipids, proteins and carbohydrates); amphipatic nature of lipids (formation of monolayers, bilayers/liposomes, and micelles); Reactions of phospholipases. Structure and properties: Models (Dawson and Danielli, Singer and Nicholson); integral (glycophorin A, anion channel ban 3, bacteriorhodopsin), lipid-anchored and peripheral (cytoskeleton of erythroid and non-erythroid cells) proteins; plasma membrane glycocalyx, antigenic properties (RBC M and N, blood group O, A and B); evidence for asymmetric, dynamic and fluid-like character of biomembranes; cell-cell recognition and fusion (eg flu virus and HIV infections); membrane biogenesis (synthesis and transport of membrane lipids). Preparation and study: Physical, chemical and biochemical methods of study (lipid bilayer and vesicles of eukaryotic and prokaryotic cells). Transport: Thermodynamics; modes (uniport, symport and antiport systems) and types (simple diffusion, passive-mediated, active, Na/K pump, co-tranport – Na/glucose pump of kidney/intestine, galactose permease of E. coli, exocytosis and endocytosis); channels (ligand gated and voltage-gated) and pores; ionophores (valinomycin, gramicidin A and nigericin).
- Credits
- 2
- Level
- Level 300
- Semester
- Semester Two
Other courses on this programme
- BCMB 301 — Intermediary Metabolism
- BCMB 302 — Cell Biology II
- BCMB 303 — Molecular Biology I
- BCMB 304 — Molecular Biology II
- BCMB 305 — Biochemistry of Hormones
- BCMB 306 — Integration and Control of Metabolism
- BCMB 307 — Data Handling & Interpretation
- BCMB 308 — Bioenergetics
- BCMB 309 — Principles of Lab Organization & Management
- BCMB 311 — Practical Biochemistry II
- BCMB 312 — Cell & Molecular Biology Practical I
- BCMB 313 — Biochemistry of Viruses
Practising BCMB 314 with Questora
Upload your own slides, notes and past papers for BCMB 314 and Questora builds mock exams, practice questions and a revision plan from them.
Start freeCourse details from University of Ghana Volume 3 Handbook for the Bachelor's Degree: Course Descriptions for Programmes in the Sciences (2017).