BCMB 308 — Bioenergetics
Biochemistry, Cell and Molecular Biology · University of Ghana
Overview of chemical thermodynamics: Internal, energy, enthalpy, entropy, Gibb‘s free energy, laws of thermodynamics; Spontaneous and non-spontaneous processes; Free energy changes in biochemistry. Principles of thermodynamics and their application to the energetics of the cell: Redox systems, electron donors and acceptors, redox couples, redox potentials, electromotive force, protonmotive forces. The concept of high energy compounds: phosphoric acid anhydrides, phosphoric-carboxylic acid anhydrides, phosphoguanidines, enolphosphates and thiol esters; basis for the high standard free energy of hydrolysis; the central role of ATP; (phosphate) group transfer potentials; substrate-level phosphorylation; energetics of coupled reactions. ATP synthesis: review of structure of mitochondrion and chloroplast; sources of energy; redox complexes for electron transport in mitochondria and in chloroplasts; establishment of proton gradients; coupling of ATP synthesis to dissipation of proton gradient; H+ -ATPase; couplers (thermogenesis). ATP utilization for the performance of cellular work; active membrane transport and mechanical work such as muscle contraction.
- Credits
- 2
- Level
- Level 300
- Semester
- Semester Two
Other courses on this programme
- BCMB 301 — Intermediary Metabolism
- BCMB 302 — Cell Biology II
- BCMB 303 — Molecular Biology I
- BCMB 304 — Molecular Biology II
- BCMB 305 — Biochemistry of Hormones
- BCMB 306 — Integration and Control of Metabolism
- BCMB 307 — Data Handling & Interpretation
- BCMB 309 — Principles of Lab Organization & Management
- BCMB 311 — Practical Biochemistry II
- BCMB 312 — Cell & Molecular Biology Practical I
- BCMB 313 — Biochemistry of Viruses
- BCMB 314 — Membrane Biochemistry
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Start freeCourse details from University of Ghana Volume 3 Handbook for the Bachelor's Degree: Course Descriptions for Programmes in the Sciences (2017).