BCMB 306 — Integration and Control of Metabolism
Biochemistry, Cell and Molecular Biology · University of Ghana
Metabolic control: Design of metabolic pathways. Regulatory enzymes fine control (allosteric, substrate/product feedback and feed-forward controls, covalent modification) and coarse control (induction and repression of enzyme synthesis). Regulation of fuel metabolism: glycolysis, gluconeogenesis, glyceroneogenesis, glycogenolysis and glycogenesis, Krebs cycle, lipogenesis and lipolysis, β-oxidation, ketogenesis, amino acid metabolism. Role of hormones (e. g. insulin, glucagon, epinephrine) and DNA binding proteins (e. g. Cyclic AMP response element binding protein (CREB), Carbohydrate response element binding protein (ChREBP), Sterol regulatory element binding protein (STREB)). Integration of metabolism: Glucose homeostasis and glucose transpoters. Interrelationships between carbohydrate, lipid, and protein metabolism. Enzyme profiles of tissues and organs. Interorgan relationships (liver, brain, muscle, adipose tissue) in different physiological states: e. g. Fed, fasted, running athlete and pregnancy.
- Credits
- 3
- Level
- Level 300
- Semester
- Semester Two
Other courses on this programme
- BCMB 301 — Intermediary Metabolism
- BCMB 302 — Cell Biology II
- BCMB 303 — Molecular Biology I
- BCMB 304 — Molecular Biology II
- BCMB 305 — Biochemistry of Hormones
- BCMB 307 — Data Handling & Interpretation
- BCMB 308 — Bioenergetics
- BCMB 309 — Principles of Lab Organization & Management
- BCMB 311 — Practical Biochemistry II
- BCMB 312 — Cell & Molecular Biology Practical I
- BCMB 313 — Biochemistry of Viruses
- BCMB 314 — Membrane Biochemistry
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Start freeCourse details from University of Ghana Volume 3 Handbook for the Bachelor's Degree: Course Descriptions for Programmes in the Sciences (2017).